Particle Creation by a Moving Boundary with Robin Boundary Condition

We consider a massless scalar field in 1+1 dimensions satisfying a Robin boundary condition (BC) at a non-relativistic moving boundary. We derive a Bogoliubov transformation between input and output bosonic field operators, which allows us to calculate the spectral distribution of created particles. The cases of Dirichlet and Neumann BC may be obtained from our result as limiting cases. These two limits yield the same spectrum, which turns out to be an upper bound for the spectra derived for Robin BC. We show that the particle emission effect can be considerably reduced (with respect to the Dirichlet/Neumann case) by selecting a particular value for the oscillation frequency of the boundary position

Hormone and receptor activator of NF-κB (RANK) pathway gene expression in plasma and mammographic breast density in postmenopausal women

BACKGROUND: Hormones impact breast tissue proliferation. Studies investigating the associations of circulating hormone levels with mammographic breast density have reported conflicting results. Due to the limited number of studies, we investigated the associations of hormone gene expression as well as their downstream mediators within the plasma with mammographic breast density in postmenopausal women. METHODS: We recruited postmenopausal women at their annual screening mammogram at Washington University School of Medicine, St. Louis. We used the NanoString nCounter platform to quantify gene expression of hormones (prolactin, progesterone receptor (PGR), estrogen receptor 1 (ESR1), signal transducer and activator of transcription (STAT1 and STAT5), and receptor activator of nuclear factor-kB (RANK) pathway markers (RANK, RANKL, osteoprotegerin, TNFRSF18, and TNFRSF13B) in plasma. We used Volpara to measure volumetric percent density, dense volume, and non-dense volume. Linear regression models, adjusted for confounders, were used to evaluate associations between gene expression (linear fold change) and mammographic breast density. RESULTS: One unit increase in ESR1, RANK, and TNFRSF18 gene expression was associated with 8% (95% CI 0-15%, p value = 0.05), 10% (95% CI 0-20%, p value = 0.04) and % (95% CI 0-9%, p value = 0.04) higher volumetric percent density, respectively. There were no associations between gene expression of other markers and volumetric percent density. One unit increase in osteoprotegerin and PGR gene expression was associated with 12% (95% CI 4-19%, p value = 0.003) and 7% (95% CI 0-13%, p value = 0.04) lower non-dense volume, respectively. CONCLUSION: These findings provide new insight on the associations of plasma hormonal and RANK pathway gene expression with mammographic breast density in postmenopausal women and require confirmation in other studies

Spatial orientation of cross-sectional images of coronary arteries: point of view in intracoronary imaging

<p>Abstract</p> <p>Background</p> <p>In studies where cross-sectional images of coronary arteries obtained with different imaging modalities are compared, the importance of correct co-localization and matching of images along the coronary artery longitudinal axis is obvious. However, it appears neglected that correct spatial orientation of the cross-sectional plane may not be obtainable just by rotating the images to ensure co-localization of identifiable landmarks such as sidebranches. A cross-section has two sides, one facing proximally and the other distally, and pairs of images reconstructed corresponding to these opposite points of view are mirror images of each other and not superimposable. This may be difficult if not impossible to recognize and unrecognized it will give rise to flawed results in the development and validation of imaging technologies aimed at plaque characterization (tissue mapping). We determined the imagined point of view for three commercially available intracoronary imaging systems used by invasive cardiologists and illustrate its importance in imaging modality validation.</p> <p>Methods and Results</p> <p>We made an asymmetric phantom and investigated it with two different intravascular ultrasound (IVUS) systems and one optical coherence tomography (OCT) system. The asymmetry of the phantom allowed determination of the spatial orientation of the cross-sectional images. On all tested systems, an observer should imagine herself/himself standing proximal to the cross-section when looking at the intravascular images.</p> <p>Conclusions</p> <p>The tested intracoronary imaging modalities displayed cross-sectional images with a spatial orientation corresponding to a proximal point of view. Knowledge of the spatial orientation is mandatory when comparing and validating different imaging modalities aimed at plaque characterization.</p

Strangeness in Astrophysics and Cosmology

Some recent developments concerning the role of strange quark matter for astrophysical systems and the QCD phase transition in the early universe are addressed. Causality constraints of the soft nuclear equation of state as extracted from subthreshold kaon production in heavy-ion collisions are used to derive an upper mass limit for compact stars. The interplay between the viscosity of strange quark matter and the gravitational wave emission from rotation-powered pulsars are outlined. The flux of strange quark matter nuggets in cosmic rays is put in perspective with a detailed numerical investigation of the merger of two strange stars. Finally, we discuss a novel scenario for the QCD phase transition in the early universe, which allows for a small inflationary period due to a pronounced first order phase transition at large baryochemical potential.Comment: 8 pages, invited talk given at the International Conference on Strangeness in Quark Matter (SQM2009), Buzios, Brasil, September 28 - October 2, 200

Double-beta decay Q values of 130Te, 128Te, and 120Te

The double-beta decay Q values of 130Te, 128Te, and 120Te have been determined from parent-daughter mass differences measured with the Canadian Penning Trap mass spectrometer. The 132Xe-129Xe mass difference, which is precisely known, was also determined to confirm the accuracy of these results. The 130Te Q value was found to be 2527.01(32) keV which is 3.3 keV lower than the 2003 Atomic Mass Evaluation recommended value, but in agreement with the most precise previous measurement. The uncertainty has been reduced by a factor of 6 and is now significantly smaller than the resolution achieved or foreseen in experimental searches for neutrinoless double-beta decay. The 128Te and 120Te Q values were found to be 865.87(131) keV and 1714.81(125) keV, respectively. For 120Te, this reduction in uncertainty of nearly a factor of 8 opens up the possibility of using this isotope for sensitive searches for neutrinoless double-electron capture and electron capture with positron emission.Comment: 5 pages, 2 figures, submitted to Physical Review Letter

National Ignition Facility environmental protection systems

The conceptual design of Environmental Protection Systems (EPS) for the National Ignition Facility (NIF) is described. These systems encompass tritium and activated debris handling, chamber, debris shield and general decontamination, neutron and gamma monitoring, and radioactive, hazardous and mixed waste handling. Key performance specifications met by EPS designs include limiting the tritium inventory to 300 Ci and total tritium release from NIF facilities to less than 10 Ci/yr. Total radiation doses attributable to NIF shall remain below 10 mrem/yr for any member of the general public and 500 mrem/yr for NIF staff. ALARA-based design features and operational procedures will, in most cases, result in much lower measured exposures. Waste minimization, improved cycle time and reduced exposures all result from the proposed CO2 robotic arm cleaning and decontamination system, while effective tritium control is achieved through a modern system design based on double containment and the proven detritiation technology

Strange quark matter in explosive astrophysical systems

Explosive astrophysical systems, such as supernovae or compact star binary mergers, provide conditions where strange quark matter can appear. The high degree of isospin asymmetry and temperatures of several MeV in such systems may cause a transition to the quark phase already around saturation density. Observable signals from the appearance of quark matter can be predicted and studied in astrophysical simulations. As input in such simulations, an equation of state with an integrated quark matter phase transition for a large temperature, density and proton fraction range is required. Additionally, restrictions from heavy ion data and pulsar observation must be considered. In this work we present such an approach. We implement a quark matter phase transition in a hadronic equation of state widely used for astrophysical simulations and discuss its compatibility with heavy ion collisions and pulsar data. Furthermore, we review the recently studied implications of the QCD phase transition during the early post-bounce evolution of core-collapse supernovae and introduce the effects from strong interactions to increase the maximum mass of hybrid stars. In the MIT bag model, together with the strange quark mass and the bag constant, the strong coupling constant $\alpha_s$ provides a parameter to set the beginning and extension of the quark phase and with this the mass and radius of hybrid stars.Comment: 6 pages, 5 figures, talk given at the International Conference on Strangeness in Quark Matter (SQM2009), Buzios, Brasil, September 28 - October 2, 2009, to be published in Journal Phys.

Simulating Dynamical Features of Escape Panic

One of the most disastrous forms of collective human behaviour is the kind of crowd stampede induced by panic, often leading to fatalities as people are crushed or trampled. Sometimes this behaviour is triggered in life-threatening situations such as fires in crowded buildings; at other times, stampedes can arise from the rush for seats or seemingly without causes. Tragic examples within recent months include the panics in Harare, Zimbabwe, and at the Roskilde rock concert in Denmark. Although engineers are finding ways to alleviate the scale of such disasters, their frequency seems to be increasing with the number and size of mass events. Yet, systematic studies of panic behaviour, and quantitative theories capable of predicting such crowd dynamics, are rare. Here we show that simulations based on a model of pedestrian behaviour can provide valuable insights into the mechanisms of and preconditions for panic and jamming by incoordination. Our results suggest practical ways of minimising the harmful consequences of such events and the existence of an optimal escape strategy, corresponding to a suitable mixture of individualistic and collective behaviour.Comment: For related information see http://angel.elte.hu/~panic, http://www.helbing.org, http://angel.elte.hu/~fij, and http://angel.elte.hu/~vicse